Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482346 | 1.00 | PIK3CA (0.37) | PIK3CAMTORSCN10ASIGMAR1FFAR2 | |
| SCHEMBL22587525 | 0.81 | ALDH1A1 (0.49) | — | |
| SCHEMBL23623071 | 0.77 | PIK3CA (0.37) | PIK3CAMTORSCN10ASIGMAR1FFAR2 | |
| SCHEMBL3435696 | 0.76 | OPRK1 (0.42) | SCN10A | |
| SCHEMBL22587574 | 0.75 | ALDH1A1 (0.51) | SCN10A | |
| SCHEMBL22803865 | 0.73 | TRPV1 (0.42) | PIK3CAMTORSCN10ASIGMAR1FFAR2 | |
| SCHEMBL30412557 | 0.73 | TRPV1 (0.42) | PIK3CAMTORSCN10ASIGMAR1FFAR2 | |
| SCHEMBL23166934 | 0.73 | SMN1; SMN2 (0.42) | PIK3CAMTORSCN10A | |
| SCHEMBL22597907 | 0.72 | GRIN2D (0.51) | SCN10AFFAR2 | |
| SCHEMBL16702878 | 0.72 | FLT3 (0.37) | PIK3CAMTORFFAR2GAKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848591-B | HDAC inhibitors and methods of making and using the same | 成都先导药物开发股份有限公司 | 2022-03-18 | — | — | CN | disclosed |