Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721490 | 1.00 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28719403 | 0.91 | ESR1 (0.55) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL29445646 | 0.91 | ESR1 (0.55) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL29445670 | 0.89 | LMNA (0.56) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL29445659 | 0.89 | ESR1 (0.51) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28723250 | 0.89 | LMNA (0.56) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28719284 | 0.89 | ESR1 (0.51) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL29445668 | 0.89 | PTGS2 (0.49) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28719397 | 0.89 | PTGS2 (0.49) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL28722315 | 0.88 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053584-B | Preparation and application of 1, 2-diaryl benzimidazole derivatives | 南京大学 | 2022-03-18 | — | — | CN | disclosed |