Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KATNA1 | O75449 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722317 | 1.00 | KDM4E (0.59) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL28719401 | 0.93 | KDM4E (0.51) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL29445624 | 0.93 | KDM4E (0.51) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL28722315 | 0.89 | KDM4E (0.59) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL29445679 | 0.89 | KDM4E (0.59) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL28721852 | 0.88 | TUBB4A (0.55) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL29445651 | 0.88 | TUBB4A (0.55) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL29445659 | 0.86 | ESR1 (0.51) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL28719397 | 0.85 | PTGS2 (0.49) | KDM4EGAAHSD17B10ALDH1A1TP53 | |
| SCHEMBL28719403 | 0.85 | ESR1 (0.55) | KDM4EHSD17B10ALDH1A1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053584-B | Preparation and application of 1, 2-diaryl benzimidazole derivatives | 南京大学 | 2022-03-18 | — | — | CN | disclosed |