Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 8/20 | 0.78 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12537305 | 0.90 | YTHDC1 (0.64) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL3395646 | 0.89 | HDAC6 (0.73) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL19539867 | 0.88 | YTHDC1 (0.74) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL27387456 | 0.87 | YTHDC1 (1.00) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL29183714 | 0.85 | YTHDC1 (0.80) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL29183741 | 0.85 | YTHDC1 (0.70) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL29445701 | 0.85 | YTHDC1 (0.72) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL17815605 | 0.84 | HDAC6 (0.62) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL29183760 | 0.84 | YTHDC1 (0.77) | YTHDC1HDAC6HDAC1HDAC4HDAC2 | |
| SCHEMBL28726438 | 0.82 | YTHDC1 (0.74) | YTHDC1HDAC6HDAC1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292269-B | O-aminopurine benzamide derivative and preparation method and application thereof | 南昌大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114292269-A | O-aminopurine benzamide derivative and preparation method and application thereof | 南昌大学 | 2022-04-08 | — | — | CN | disclosed |