Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.96 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262139 | 1.00 | KDM4E (0.96) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1131200 | 1.00 | KDM4E (0.96) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| Acetic Acid SCHEMBL8841092 | 0.91 | KDM4E (0.81) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| Acetic Acid SCHEMBL8841087 | 0.91 | KDM4E (0.81) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7875715 | 0.89 | KDM4E (0.77) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7875720 | 0.89 | KDM4E (0.77) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153586 | 0.88 | KDM4E (0.75) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153584 | 0.88 | KDM4E (0.75) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7103304 | 0.84 | KDM4E (0.69) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153290 | 0.84 | KDM4E (0.69) | KDM4ELMNAMAPK1SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265528-B | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2015-05-06 | — | — | CN | claimed |
| CN-103265528-A | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-1331835-C | Preparation method of optically active beta-hydroxy ketone | UNIV WUHAN (CN) | 2007-08-15 | — | — | CN | claimed |
| CN-1785950-A | Preparation method of optically active beta-hydroxy ketone | UNIV WUHAN (CN) | 2006-06-14 | — | — | CN | claimed |
| CN-105339352-B | The method that pyrazolecarboxamide is prepared for stereoselectivity | 先正达参股股份有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-105339352-A | Process for the stereoselective preparation of a pyrazole-carboxamide | SYNGENTA PARTICIPATIONS AG | 2016-02-17 | — | — | CN | disclosed |
| US-9175006-B2 | Compositions and methods for cyclofructans as separation agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-03 | — | — | US | disclosed |
| US-9175006-B2 | Compositions and methods for cyclofructans as separation agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-03 | — | — | US | disclosed |
| US-9175006-B2 | Compositions and methods for cyclofructans as separation agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-03 | — | — | US | disclosed |
| CN-103265528-B | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2015-05-06 | — | — | CN | disclosed |
| US-8759555-B2 | Stereoselective synthesis of vitamin D analogues | LEO PHARMA A/S (DK) | 2014-06-24 | — | — | US | disclosed |
| CN-103265528-A | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2013-08-28 | — | — | CN | disclosed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | disclosed |
| EP-0305180-B1 | Enantioselective reduction of ketones | HARVARD COLLEGE (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0485069-B1 | Process for producing optically active amines | SUMITOMO CHEMICAL CO (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-4943635-A | OXAZABOROLIDINES AND OXAZABORINES AS CATALYSTS | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0305180-A2 | Enantioselective reduction of ketones | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-03-01 | — | — | EP | disclosed |
| EP-0075868-A2 | Optically active amino alcohols and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |