Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.96 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294458 | 1.00 | KDM4E (0.96) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1262139 | 1.00 | KDM4E (0.96) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| Acetic Acid SCHEMBL8841092 | 0.91 | KDM4E (0.81) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| Acetic Acid SCHEMBL8841087 | 0.91 | KDM4E (0.81) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7875715 | 0.89 | KDM4E (0.77) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7875720 | 0.89 | KDM4E (0.77) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153586 | 0.88 | KDM4E (0.75) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153584 | 0.88 | KDM4E (0.75) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL7103304 | 0.84 | KDM4E (0.69) | KDM4ELMNAMAPK1EPHX1ANPEP | |
| SCHEMBL1153290 | 0.84 | KDM4E (0.69) | KDM4ELMNAMAPK1SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265528-B | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2015-05-06 | — | — | CN | claimed |
| CN-103265528-A | Esomeprazole magnesium preparation method | HUNAN QIANJIN XIANGJIANG PHARM CO LTD | 2013-08-28 | — | — | CN | claimed |
| US-8471067-B2 | Stereoselective preparation of P-chiral four-co-ordinated phosphorus compound (o-Tolylphenylmethylphosphine oxide) by reacting chiral alcohol, chiral amine or chiral thiol, with P-chiral three-co-ordinated phosphorus compound, in presence of electrophile | UNIVERSITY COLLEGE DUBLIN (IE) | 2013-06-25 | — | — | US | claimed |
| US-20080255391-A1 | Chiral Phosphorus Compounds | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND (IE) | 2008-10-16 | — | — | US | claimed |
| US-10788471-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-10012627-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-10012627-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-9815746-B2 | Stereodynamic chemosensors | GEORGETOWN UNIVERSITY (US) | 2017-11-14 | — | — | US | disclosed |
| US-9815746-B2 | Stereodynamic chemosensors | GEORGETOWN UNIVERSITY (US) | 2017-11-14 | — | — | US | disclosed |
| US-20160039723-A1 | STEREODYNAMIC CHEMOSENSORS | GEORGETOWN UNIVERSITY (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160039723-A1 | STEREODYNAMIC CHEMOSENSORS | GEORGETOWN UNIVERSITY (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160011156-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2016-01-14 | — | — | US | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6072081-A | Optically active bisoxazoline compounds, production and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-06 | — | — | US | disclosed |
| US-6025531-A | REACTING A PROCHIRAL KETONE WITH A MIXTURE BORON-CONTAINING COMPOUNDS HAVING A BORANE REACTION PRODUCT FROM OPTICALLY ACTIVE BETA-AMINOALCOHOL AND A BORON HYDRIDE OR A METAL BOROHYDRIDE, AND AN OPTICALLY ACTIVE OXAZABOROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5801280-A | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-01 | — | — | US | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0736509-A2 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039723-A1 | STEREODYNAMIC CHEMOSENSORS | ENO1, EDNRA, OPRL1 | KDM4E 4547/4885LMNA 4292/4885MAPK1 2548/4885 |
| US-20080255391-A1 | Chiral Phosphorus Compounds | PHOSPHO1, PNKP, PTMS | KDM4E 4137/4885LMNA 3952/4885MAPK1 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.