Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982877 | 1.00 | HTR1A (0.36) | HTR1ADRD2CA12BRD4BRPF1 | |
| SCHEMBL4999235 | 0.81 | HTR1A (0.38) | HTR1ADRD2CA12BRD4BRPF1 | |
| SCHEMBL4360956 | 0.73 | HTR1A (0.39) | HTR1A | |
| SCHEMBL30832178 | 0.72 | MCL1 (0.52) | — | |
| SCHEMBL9272471 | 0.69 | — | — | |
| SCHEMBL1650468 | 0.69 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL3125224 | 0.68 | PARP1 (0.37) | HTR1A | |
| SCHEMBL25193535 | 0.67 | KDM4E (0.31) | — | |
| SCHEMBL6173719 | 0.67 | HDAC6 (0.32) | HTR1ADRD2 | |
| SCHEMBL8905089 | 0.67 | KDM4E (0.38) | HTR1ADRD2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306604-A | Use of farnesyl transferase inhibitors for the treatment of cancer | 库拉肿瘤学公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110325212-B | Farnesyl transferase inhibitors for use in methods of treating cancer | 库拉肿瘤学公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114107497-A | Use of farnesyl transferase inhibitors for the treatment of cancer | 库拉肿瘤学公司 | 2022-03-01 | — | — | CN | disclosed |