Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982877 | 0.72 | HTR1A (0.36) | — | |
| SCHEMBL29445869 | 0.72 | HTR1A (0.36) | — | |
| SCHEMBL30430299 | 0.70 | MCL1 (0.43) | MCL1FDPSDAOCCR2ALDH1A1 | |
| SCHEMBL2347010 | 0.69 | MCL1 (0.83) | MCL1FDPSDAOCCR2ALDH1A1 | |
| SCHEMBL6330126 | 0.67 | MCL1 (0.46) | MCL1FDPSDAOCCR2ALDH1A1 | |
| SCHEMBL3064664 | 0.67 | MCL1 (1.00) | MCL1FDPSCCR2ALDH1A1KDM4E | |
| SCHEMBL11967620 | 0.65 | MCL1 (0.34) | MCL1ALDH1A1TSHRKDM4E | |
| SCHEMBL22687067 | 0.65 | MCL1 (0.57) | MCL1FDPSDAOCCR2ALDH1A1 | |
| SCHEMBL30419432 | 0.65 | MCL1 (0.48) | MCL1FDPSDAOALDH1A1KDM4E | |
| SCHEMBL25503879 | 0.65 | MCL1 (0.48) | MCL1FDPSDAOALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865878-A | Chiral indoline-3-one derivative and preparation method thereof | 郑州大学 | 2024-04-12 | — | — | CN | disclosed |