SCHEMBL29446191

SCHEMBL29446191

CCCOc1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(CC)n(Cc3ccccn3)nc2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 20/20 1.00
PDE6C P51160 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028938 1.00 PDE5A (1.00) PDE5APDE6C
SCHEMBL316656 1.00 PDE5A (1.00) PDE5APDE6C
SCHEMBL5595647 0.95 PDE5A (0.91) PDE5APDE6C
SCHEMBL6333003 0.94 PDE5A (0.90) PDE5APDE6C
SCHEMBL6340439 0.94 PDE5A (0.88) PDE5APDE6C
SCHEMBL6334181 0.93 PDE5A (0.87) PDE5APDE6C
SCHEMBL6338367 0.92 PDE5A (0.86) PDE5APDE6C
Citric Acid SCHEMBL6332216 0.92 PDE5A (0.85) PDE5APDE6C
SCHEMBL6340273 0.92 PDE5A (0.85) PDE5APDE6C
SCHEMBL6332752 0.91 PDE5A (0.83) PDE5APDE6C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408090-A1 Methods Of Treating Dyskinesia And Related Disorders MELIOR PHARMACEUTICALS II, LLC 2024-12-12 US claimed
US-12048697-B2 Methods of treating dyskinesia and related disorders MELIOR PHARMACEUTICALS II, LLC (US) 2024-07-30 US claimed
US-20220331320-A1 Methods Of Treating Dyskinesia And Related Disorders MELIOR PHARMACEUTICALS II, LLC 2022-10-20 US claimed
WO-2026107071-A1 COMBINATION THERAPY Retension Pharmaceuticals, Inc. (US) 2026-05-21 WO disclosed
US-20250073171-A1 DRUG DELIVERY SYSTEM FOR THE TREATMENT OF FEMALE SEXUAL INTEREST AND AROUSAL DISORDER Freya Pharma Solutions Holding B.V. (NL) 2025-03-06 US disclosed
US-20240408090-A1 Methods Of Treating Dyskinesia And Related Disorders MELIOR PHARMACEUTICALS II, LLC 2024-12-12 US disclosed
US-12048697-B2 Methods of treating dyskinesia and related disorders MELIOR PHARMACEUTICALS II, LLC (US) 2024-07-30 US disclosed
US-20240165032-A1 DRUG DELIVERY SYSTEM EB IP HYBRITABS B V (NL) 2024-05-23 US disclosed
EP-3806888-B1 PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY OBSIDIAN THERAPEUTICS INC (US) 2024-01-31 EP disclosed
US-20230330028-A1 PROCESS FOR THE PREPARATION OF DRUG DELIVERY SYSTEMS HAVING A TESTOSTERONE COMPOUND PRESENT IN AN OUTER LAYER OR PART, AS WELL AS SUCH DRUG DELIVERY SYSTEMS EB IP HYBRITABS B.V. (NL) 2023-10-19 US disclosed
US-11666642-B2 PDE5 compositions and methods for immunotherapy OBSIDIAN THERAPEUTICS, INC. (US) 2023-06-06 US disclosed
US-20230056856-A1 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF TRANSCRIPTION OBSIDIAN THERAPEUTICS, INC. (US) 2023-02-23 US disclosed
US-20220403001-A1 PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY OBSIDIAN THERAPEUTICS, INC. (US) 2022-12-22 US disclosed
CN-109414402-B Method for preparing a drug delivery system with a testosterone compound present externally or topically and such a drug delivery system EB IP希博里塔布斯有限责任公司 2022-11-04 CN disclosed
US-20220331320-A1 Methods Of Treating Dyskinesia And Related Disorders MELIOR PHARMACEUTICALS II, LLC 2022-10-20 US disclosed
US-20220175781-A1 CD40L COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OBSIDIAN THERAPEUTICS, INC. (US) 2022-06-09 US disclosed
US-11351169-B2 Methods of treating dyskinesia and related disorders MELIOR PHARMACEUTICALS II, LLC (US) 2022-06-07 US disclosed
US-20220170011-A1 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF CAS NUCLEASES OBSIDIAN THERAPEUTICS, INC. (US) 2022-06-02 US disclosed
CN-114174327-A Compositions and methods for adjustable modulation of CD40L 黑曜石疗法公司 2022-03-11 CN disclosed
US-11241485-B2 PDE5 compositions and methods for immunotherapy OBSIDIAN THERAPEUTICS, INC. (US) 2022-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220331320-A1 Methods Of Treating Dyskinesia And Related Disorders SLC6A3, CHAT, ACHE PDE5A 161/4885PDE6C 194/4885
US-20240408090-A1 Methods Of Treating Dyskinesia And Related Disorders SLC6A3, CHAT, ACHE PDE5A 161/4885PDE6C 194/4885
US-12048697-B2 Methods of treating dyskinesia and related disorders SLC6A3, CHAT, ACHE PDE5A 161/4885PDE6C 194/4885
US-11351169-B2 Methods of treating dyskinesia and related disorders SLC6A3, CHAT, ACHE PDE5A 161/4885PDE6C 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.