⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481422 | 0.93 | ALDH1A1 (0.33) | — | |
| SCHEMBL15342 | 0.93 | — | — | |
| SCHEMBL6135207 | 0.86 | ALDH1A1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL7066020 | 0.86 | — | — | |
| SCHEMBL423855 | 0.86 | — | — | |
| SCHEMBL8853785 | 0.86 | ALDH1A1 (0.30) | — | |
| SCHEMBL6135760 | 0.86 | ALDH1A1 (0.30) | — | |
| SCHEMBL504312 | 0.86 | — | — | |
| SCHEMBL22973418 | 0.86 | — | — | |
| SCHEMBL3432651 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459764-A | Preparation method of acrylic acid grafted modified methylphenyl polysiloxane prepolymer and application of acrylic acid grafted modified methylphenyl polysiloxane prepolymer in 3D printing photosensitive resin | 泉州师范学院 | 2024-08-09 | — | — | CN | disclosed |
| US-20240018138-A1 | PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | VENTUS THERAPEUTICS U.S., INC. | 2024-01-18 | — | — | US | disclosed |
| EP-4263520-A1 | HETEROCYCLIC INHIBITORS OF PCSK9 | Cardio Therapeutics Pty Ltd (AU) | 2023-10-25 | — | — | EP | disclosed |
| EP-4216940-A1 | PYRIDO[4,3-B]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Ventus Therapeutics U.S., Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022133529-A1 | HETEROCYCLIC INHIBITORS OF PCSK9 | Cardio Therapeutics Pty Ltd (AU) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022066851-A1 | PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | VENTUS THERAPEUTICS U.S., INC. (US) | 2022-03-31 | — | — | WO | disclosed |