⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324015 | 1.00 | — | — | |
| SCHEMBL22323949 | 0.77 | ENPP2 (0.43) | — | |
| SCHEMBL29447077 | 0.77 | ENPP2 (0.43) | — | |
| SCHEMBL27382522 | 0.73 | TP53 (0.45) | — | |
| SCHEMBL11232353 | 0.73 | PIK3CD (0.51) | — | |
| SCHEMBL29486354 | 0.73 | ENPP2 (0.54) | — | |
| SCHEMBL29486357 | 0.73 | ENPP2 (0.54) | — | |
| SCHEMBL25439911 | 0.71 | ENPP2 (0.44) | — | |
| SCHEMBL13737306 | 0.69 | ESR1 (0.43) | — | |
| SCHEMBL22325389 | 0.67 | MAPT (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |