Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323949 | 1.00 | ENPP2 (0.43) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16051759 | 0.78 | NOTUM (0.42) | ENPP2ALDH1A1HCRTR1HCRTR2MAPK1 | |
| SCHEMBL27899616 | 0.77 | MEN1 (0.39) | ALDH1A1HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL22324015 | 0.77 | — | — | |
| SCHEMBL29447124 | 0.77 | — | — | |
| SCHEMBL22323697 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL15476234 | 0.75 | CYP11B1 (0.55) | ENPP2CYP3A4 | |
| SCHEMBL31605135 | 0.74 | MAPK1 (0.43) | ALDH1A1HCRTR1HCRTR2CYP3A4GAA | |
| SCHEMBL25173988 | 0.72 | ENPP2 (0.54) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22324022 | 0.72 | HCRTR1 (0.36) | ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |