Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950599 | 0.89 | BDKRB1 (0.74) | BDKRB1CNR1 | |
| SCHEMBL2944726 | 0.80 | BDKRB1 (0.56) | BDKRB1CNR1 | |
| SCHEMBL2949488 | 0.78 | BDKRB1 (0.71) | BDKRB1CNR1 | |
| SCHEMBL13213721 | 0.77 | BDKRB1 (0.82) | BDKRB1CNR1 | |
| SCHEMBL2943307 | 0.76 | FFAR1 (0.45) | BDKRB1CNR1 | |
| Hydrochloric Acid SCHEMBL2943098 | 0.75 | FFAR1 (0.45) | BDKRB1CNR1 | |
| SCHEMBL5929429 | 0.72 | BDKRB1 (0.73) | BDKRB1CNR1 | |
| SCHEMBL2944724 | 0.71 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL2946704 | 0.70 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL5929278 | 0.70 | BDKRB1 (0.76) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |