Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.87 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393260 | 0.98 | LTA4H (0.84) | LTA4HHRH3SLC6A3HTTSIGMAR1 | |
| SCHEMBL22440218 | 0.93 | LTA4H (0.77) | LTA4HHRH3SLC6A3HTTSIGMAR1 | |
| SCHEMBL26981197 | 0.92 | LTA4H (0.75) | LTA4HHRH3SLC6A3HTTSIGMAR1 | |
| SCHEMBL19557301 | 0.92 | LTA4H (0.75) | LTA4HHRH3SLC6A3HTTSIGMAR1 | |
| SCHEMBL27540109 | 0.90 | LTA4H (0.72) | LTA4HHRH3HTTSIGMAR1NPC1 | |
| SCHEMBL31305362 | 0.89 | LTA4H (0.71) | LTA4HHRH3SLC6A3SIGMAR1RAB9A | |
| SCHEMBL27533341 | 0.89 | LTA4H (0.70) | LTA4HHRH3HTTSIGMAR1NPC1 | |
| SCHEMBL13940618 | 0.87 | LTA4H (0.68) | LTA4HHRH3HTTSIGMAR1NPC1 | |
| SCHEMBL7388780 | 0.86 | LTA4H (0.67) | LTA4HHRH3SLC6A3HTTSIGMAR1 | |
| SCHEMBL2650781 | 0.84 | LTA4H (0.65) | LTA4HHRH3SLC6A3HTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | SCN1A, SCN1B, SCN2B | LTA4H 1555/4885HRH3 1685/4885SLC6A3 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.