Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPY1R | P25929 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22440218 | 0.92 | LTA4H (0.77) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL6393260 | 0.90 | LTA4H (0.84) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL29447351 | 0.89 | LTA4H (0.87) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7388987 | 0.86 | LTA4H (0.56) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7389601 | 0.86 | LTA4H (0.56) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7387110 | 0.84 | LTA4H (0.57) | LTA4HHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7400511 | 0.84 | KDM4E (0.85) | LTA4HHRH3KDM4EALDH1A1NPY1R | |
| SCHEMBL7399833 | 0.84 | KDM4E (0.85) | LTA4HHRH3KDM4EALDH1A1NPY1R | |
| SCHEMBL7400512 | 0.84 | KDM4E (0.85) | LTA4HHRH3KDM4EALDH1A1NPY1R | |
| SCHEMBL7397895 | 0.84 | KDM4E (0.85) | LTA4HHRH3KDM4EALDH1A1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1292789-A | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AWANDIS PHARMACEUTICAL CORP (US) | 2001-04-25 | — | — | CN | disclosed |