Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP7 | P09237 | 4/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627723 | 1.00 | ALDH1A1 (0.42) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL28540528 | 1.00 | ALDH1A1 (0.42) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL29447378 | 0.93 | ALDH1A1 (0.41) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL19627721 | 0.93 | ALDH1A1 (0.41) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL28556812 | 0.92 | ALDH1A1 (0.42) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL30845610 | 0.92 | ALDH1A1 (0.42) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL21789465 | 0.92 | ALDH1A1 (0.42) | ALDH1A1STSMMP1MMP9MMP3 | |
| SCHEMBL19614262 | 0.91 | MMP9 (0.39) | MMP1MMP9BMP1MMP13 | |
| SCHEMBL19614263 | 0.91 | MMP9 (0.39) | MMP1MMP9BMP1MMP13 | |
| SCHEMBL19627654 | 0.90 | SCN1A (0.44) | ALDH1A1STSMMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | SCN1A, SCN1B, SCN2B | ALDH1A1 2797/4885STS 181/4885MMP1 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.