⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247296 | 1.00 | — | — | |
| SCHEMBL25816669 | 0.73 | — | — | |
| SCHEMBL27215066 | 0.72 | NQO1 (0.43) | — | |
| SCHEMBL29705335 | 0.72 | NQO1 (0.43) | — | |
| SCHEMBL16389765 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL31312260 | 0.68 | CTSS (0.39) | — | |
| SCHEMBL22456038 | 0.68 | — | — | |
| SCHEMBL16094561 | 0.68 | MEN1 (0.34) | — | |
| SCHEMBL353390 | 0.67 | — | — | |
| SCHEMBL16094819 | 0.67 | BRAF (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378218-B2 | Cyclopentane compounds | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-08-05 | — | — | US | disclosed |
| US-20250230155-A1 | 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | VANDERBILT UNIVERSITY | 2025-07-17 | — | — | US | disclosed |
| CN-117534670-A | Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders | 加拉帕戈斯股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20220194922-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2022-06-23 | — | — | US | disclosed |
| US-11274091-B2 | Cyclopentane compounds | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-03-15 | — | — | US | disclosed |