Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974633 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL21731327 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL21742925 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL21731326 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL23958019 | 0.84 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL4590329 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL24297817 | 0.81 | HTR1A (0.52) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL21722767 | 0.80 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL23521672 | 0.80 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A | |
| SCHEMBL21722768 | 0.80 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206859-B | 3-Aryloxy-3-five-membered heteroaryl-propylamine compound, and crystal forms and application thereof | 上海璃道医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112566909-B | 3-aryloxy-3-five-membered heteroaryl-propylamine compound and application thereof | 上海璃道医药科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-114206859-A | 3-aryloxy-3-pentabasic heteroaryl-propylamine compound and crystal form and application thereof | 上海璃道医药科技有限公司 | 2022-03-18 | — | — | CN | disclosed |