Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731327 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL29447472 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL29974633 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL21731326 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL21742925 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL24604592 | 0.77 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL21742921 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL22660734 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL21731325 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL29447463 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332035-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332035-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | TRPV1, TRPA1, TRPM5 | SLC6A2 238/4885SLC6A4 137/4885SLC6A3 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.