SCHEMBL29448477

SCHEMBL29448477

CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(Cl)nc3[nH]cc(Cl)c23)C1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BTK Q06187 19/20 0.54
JAK3 P52333 18/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22496749 1.00 BTK (0.54) BTKJAK3
SCHEMBL22497106 1.00 BTK (0.54) BTKJAK3
SCHEMBL29944782 0.94 BTK (0.54) BTKJAK3
SCHEMBL28918226 0.92 JAK3 (0.52) BTKJAK3
SCHEMBL29448486 0.92 JAK3 (0.52) BTKJAK3
SCHEMBL29448485 0.92 JAK3 (0.52) BTKJAK3
SCHEMBL22496733 0.92 JAK3 (0.52) BTKJAK3
SCHEMBL22496761 0.88 JAK3 (0.53) BTKJAK3
SCHEMBL29448488 0.88 JAK3 (0.53) BTKJAK3
SCHEMBL28599694 0.85 JAK3 (0.58) BTKJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4656249-A2 PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR Daewoong Pharmaceutical Co., Ltd. (KR) 2025-12-03 EP disclosed
EP-3478687-B1 PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR DAEWOONG PHARMACEUTICAL CO LTD (KR) 2024-03-20 EP disclosed
EP-3950691-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR Daewoong Pharmaceutical Co., Ltd. (KR) 2022-02-09 EP disclosed