SCHEMBL29448530

SCHEMBL29448530

Nc1cccc2c(=O)[nH][nH]c(=O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
PARP1 P09874 8/20 0.47
TDP1 Q9NUW8 3/20 0.47
RECQL P46063 2/20 0.47
JAK2 O60674 1/20 0.46
RPS6KA3 P51812 1/20 0.46
MELK Q14680 1/20 0.46
STK24 Q9Y6E0 1/20 0.46
ALOX5 P09917 1/20 0.45
CYP3A4 P08684 2/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DAO P14920 1/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
TYMS P04818 1/20 0.41
AURKA O14965 2/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20086 1.00 ALDH1A1 (1.00) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL27034083 1.00 ALDH1A1 (1.00) ALDH1A1PARP1TDP1RECQLJAK2
Potassium SCHEMBL1315293 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Water SCHEMBL18317911 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL1316616 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL25429670 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL1315230 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Hydrochloric Acid SCHEMBL7117065 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL49588 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Lithium SCHEMBL1315235 0.98 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067689-A1 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE FOR THE TREATMENT OF INFECTIONS WITH AN RNA VIRUS METRIOPHARM AG (CH) 2025-04-03 WO claimed
EP-4499062-A1 COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AND A FUMARIC ACID ESTER MetrioPharm AG (CH) 2025-02-05 EP claimed
CN-116075306-B Compounds for the treatment of coronavirus infections 麦翠奥制药公司 2024-12-27 CN claimed
CN-118973563-A Combination of 5-amino-2, 3-dihydro-1, 4-phthalazinedione with fumarate 麦翠奥制药公司 2024-11-15 CN claimed
EP-4460312-A1 COMBINATION OF BUDESONIDE AND 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE MetrioPharm AG (CH) 2024-11-13 EP claimed
CN-118785909-A Use of 5-amino-2, 3-dihydro-1, 4-phthalazinediones for the treatment of congenital muscular dystrophy 麦翠奥制药公司 2024-10-15 CN claimed
CN-118510521-A Combination of budesonide and 5-amino-2, 3-dihydro-1, 4-phthalazinedione 麦翠奥制药公司 2024-08-16 CN claimed
CN-118369100-A Combination of 5-amino-2, 3-dihydro-1, 4-phthalazinedione with 6' -methoxy cinchonine-9-ol for the treatment of coronavirus infections 麦翠奥制药公司 2024-07-19 CN claimed
CN-111587243-B Method for solubilising 5-amino-2, 3-dihydro-1, 4-phthalazinediones 麦翠奥制药公司 2024-04-12 CN claimed
CN-111107839-B Microneedle array with color transition indicator LTS勒曼治疗系统股份公司 2023-11-10 CN claimed
EP-4164651-A1 COMPOUND FOR THE TREATMENT OF CORONAVIRAL INFECTIONS MetrioPharm AG (CH) 2023-04-19 EP claimed
CN-115916258-A Glucocorticoid reducing agent 麦翠奥制药公司 2023-04-04 CN claimed
EP-4125802-A1 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE FOR TREATMENT OF ACUTE LUNG INJURY MetrioPharm AG (CH) 2023-02-08 EP claimed
EP-4096628-A1 USE OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE IN THE INHALATORY TREATMENT OF INFLAMMATORY PULMONARY DISEASES MetrioPharm AG (CH) 2022-12-07 EP claimed
EP-4096669-A1 USE OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE IN THE TREATMENT OF RARE CHRONIC INFLAMMATORY PULMONARY DISEASES MetrioPharm AG (CH) 2022-12-07 EP claimed
WO-2022245969-A1 IRON ION DETECTING ASPIRATING DENTAL CARTRIDGE SYSTEM ACIES MEDICAL LLC (US) 2022-11-24 WO claimed
CN-115052602-A Use of 5-amino-2, 3-dihydro-1, 4-phthalazinediones in the treatment of rare chronic inflammatory lung diseases 麦翠奥制药公司 2022-09-13 CN claimed
CN-109071461-B Method for preparing 5-amino-2, 3-dihydrophthalazine-1, 4-diketone crystal 麦翠奥制药公司 2022-06-21 CN claimed
WO-2022117221-A1 LUMINOL FOR THE PROPHYLAXIS AND THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2022-06-09 WO claimed
WO-2022120383-A1 METHOD FOR DETECTION OF VIRAL INFECTIONS USING SPLIT ENZYMES BRIGHAM YOUNG UNIVERSITY (US) 2022-06-09 WO claimed