SCHEMBL49588

SCHEMBL49588

Nc1cccc2c(=O)[nH][nH]c(=O)c12.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.96
PARP1 P09874 8/20 0.46
TDP1 Q9NUW8 3/20 0.46
RECQL P46063 2/20 0.46
JAK2 O60674 1/20 0.44
RPS6KA3 P51812 1/20 0.44
MELK Q14680 1/20 0.44
STK24 Q9Y6E0 1/20 0.44
ALOX5 P09917 1/20 0.43
KDM4E B2RXH2 2/20 0.42
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
DAO P14920 1/20 0.42
CYP3A4 P08684 2/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TYMS P04818 1/20 0.40
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25429670 1.00 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Water SCHEMBL28570725 0.98 ALDH1A1 (0.92) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL27034083 0.98 ALDH1A1 (1.00) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL20086 0.98 ALDH1A1 (1.00) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL29448530 0.98 ALDH1A1 (1.00) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL1315230 0.96 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Potassium SCHEMBL1315293 0.96 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Hydrochloric Acid SCHEMBL7117065 0.96 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
Water SCHEMBL18317911 0.96 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2
SCHEMBL1316616 0.96 ALDH1A1 (0.96) ALDH1A1PARP1TDP1RECQLJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081324-A1 CHEMILUMINESCENCE REACTION DETECTION REAGENT AND DETECTION METHOD FOR CONTENT OF SPERMINE IN SEMINAL PLASMA 华北理工大学 2025-04-24 WO claimed
CN-118085031-A Biological probe based on enzyme peptide self-assembly and application thereof in detection of OTA 江南大学 2024-05-28 CN claimed
CN-117903785-A Preparation method of transition metal-based luminol nano composite self-luminous material and application of transition metal-based luminol nano composite self-luminous material in light driving treatment of tumors 南京师范大学 2024-04-19 CN claimed
US-20240075029-A1 LUMINOL FOR THE PROPHYLAXIS AND THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2024-03-07 US claimed
US-20240041763-A1 APPARATUS AND METHOD FOR PROTECTING NEURONS AND REDUCING INFLAMMATION AND SCARRING GALEN THERAPEUTICS LLC 2024-02-08 US claimed
EP-4096628-B1 USE OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE IN THE INHALATORY TREATMENT OF INFLAMMATORY PULMONARY DISEASES METRIOPHARM AG (CH) 2024-01-24 EP claimed
WO-2023224983-A1 COMPOSITION FOR THE DETECTION AND PARTIAL DECONTAMINATION OF CHEMICAL THREAT AGENTS ON SKIN SURFACE FOLLOWING DERMAL EXPOSURE THE UNITED STATES GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2023-11-23 WO claimed
EP-4255391-A1 LUMINOL FOR THE PROPHYLAXIS AND THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION MetrioPharm AG (CH) 2023-10-11 EP claimed
WO-2023179905-A1 COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AND A FUMARIC ACID ESTER METRIOPHARM AG (CH) 2023-09-28 WO claimed
EP-4248963-A1 COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A FUMARIC ACID ESTER MetrioPharm AG (CH) 2023-09-27 EP claimed
WO-2010091257-A1 PHARMACEUTICAL GRADE PHTHALAZINEDIONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BACH PHARMA, INC. (US) 2010-08-12 WO claimed
WO-2010082858-A2 NEW METHOD FOR OBTAINING 5-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE ALKALI METAL SALTS AND THEIR USE IN MEDICINE ABIDOPHARMA PL SP. Z.O.O (PL) 2010-07-22 WO claimed
CN-101221170-A High-efficiency enzyme promoted chemiluminescence substrate system SHENZHEN HUAYING BIOTECHNOLOGY (CN) 2008-07-16 CN claimed
US-20020198208-A1 MEDICINAL PREPARATION AND PROCESS FOR MANUFACTURING THEREOF ABIDOV, MUSA TAZHUDINOVICH (RU) 2002-12-26 US claimed
US-20020192736-A1 Assay of peroxidase activity PIERCE CHEMICAL COMPANY 2002-12-19 US claimed
US-6489326-B1 SODIUM NUCLEINATE, 2-AMINO-1,2,3,4-TETRAHYDROPHTHALAZINE-1,4-DIONE SODIUM SALT DIHYDRATE, USED AS AN IMMUNOMODULATOR, WHICH ALSO HAS ANTIINFLAMMATORY AND ANTIOXIDANT PROPERTIES Pavlov, Anatoliy Ivanovich (RU) 2002-12-03 US claimed
EP-0898620-B1 ASSAY OF PEROXIDASE ACTIVITY PIERCE CHEMICAL CO (US) 2002-11-06 EP claimed
EP-1203587-A1 A MEDICAMENT AND METHOD FOR THE PRODUCTION THEREOF Abidov, Musea Tazhudinovich (RU) 2002-05-08 EP claimed
EP-0898620-A1 ASSAY OF PEROXIDASE ACTIVITY PIERCE CHEMICAL COMPANY (US) 1999-03-03 EP claimed
WO-1997039142-A1 ASSAY OF PEROXIDASE ACTIVITY PIERCE CHEMICAL COMPANY (US) 1997-10-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240041763-A1 APPARATUS AND METHOD FOR PROTECTING NEURONS AND REDUCING INFLAMMATION AND SCARRING MPO, MMP8, GPX1 ALDH1A1 1160/4885PARP1 1961/4885TDP1 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.