Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519875 | 0.87 | KCNH2 (0.62) | KCNH2KMT2AMEN1LMNAMGLL | |
| SCHEMBL11521416 | 0.86 | MGLL (0.54) | KCNH2MGLLMAOBHRH3HTR2A | |
| SCHEMBL9726195 | 0.86 | HTR2A (0.69) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL8313722 | 0.86 | KCNH2 (0.71) | KCNH2HRH3HTR2AKDM4ECYP1A2 | |
| SCHEMBL11744859 | 0.82 | KCNH2 (0.55) | KCNH2MGLLMAOBHRH3HTR2A | |
| SCHEMBL11516583 | 0.82 | HTR2A (0.70) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL6378462 | 0.80 | NPC1 (0.58) | KMT2AMEN1DRD4LMNATSHR | |
| SCHEMBL29448590 | 0.79 | KCNH2 (0.69) | KCNH2KMT2AMEN1DRD4DRD3 | |
| SCHEMBL28203216 | 0.79 | KMT2A (0.71) | KCNH2KMT2AMEN1DRD4DRD3 | |
| SCHEMBL10340074 | 0.78 | KCNH2 (0.86) | KCNH2HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |