SCHEMBL29449359

SCHEMBL29449359

Nc1cccc(N(c2ccccc2)c2ccccc2)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.46
CYP3A4 P08684 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 5/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CD44 P16070 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALOX15 P16050 2/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
NPC1 O15118 2/20 0.34
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278360 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL30221915 0.84 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL388104 0.84 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL6859694 0.83 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL1995638 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL2465784 0.81 ALDH1A1 (0.37) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL29177945 0.80 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL5493729 0.79 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL29595956 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4TDP1MAPTL3MBTL1
SCHEMBL16848498 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4TDP1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111556883-B Polyimide film having improved alkali resistance and method for preparing the same 韩国爱思开希可隆PI股份有限公司 2022-12-23 CN disclosed
CN-109426121-B Endless belt, image forming apparatus, endless belt unit, and polyimide resin molded article 富士胶片商业创新有限公司 2022-09-16 CN disclosed
CN-114929474-A Flexible metal-clad laminated board with microstrip line structure 株式会社钟化 2022-08-19 CN disclosed
CN-107709424-B Systems and methods for producing aerogel materials 气凝胶科技有限责任公司 2022-08-02 CN disclosed
CN-114133359-A Diamine compound, method for preparing the same, and composition comprising the same SK新技术株式会社 2022-03-04 CN disclosed
CN-114133563-A Polyimide precursor, polyimide precursor composition, polyimide film, method for producing same, and use thereof SK新技术株式会社 2022-03-04 CN disclosed