SCHEMBL2465784

SCHEMBL2465784

Nc1cccc(N(N)c2ccccc2)c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.37
CYP3A4 P08684 5/20 0.37
TSHR P16473 5/20 0.37
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
CD44 P16070 1/20 0.37
ALOX15 P16050 2/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83274 0.85 CYP3A4 (0.41) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL27897032 0.83 CYP3A4 (0.35) ALDH1A1CYP3A4TDP1ALOX15CASP1
SCHEMBL29449359 0.81 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL1278360 0.81 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL28074701 0.80 CD44 (0.43) ALDH1A1CYP3A4TSHRTDP1CD44
Methyl Alcohol SCHEMBL27475139 0.79 CYP3A4 (0.36) ALDH1A1CYP3A4TSHRHPGDHSD17B10
Fluoromethane SCHEMBL27860810 0.79 CYP3A4 (0.36) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL31207304 0.78 CD44 (0.40) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL17739024 0.77 LOXL2 (0.35) ALDH1A1CYP3A4TSHRHPGDHSD17B10
SCHEMBL7547509 0.76 ALDH1A1 (0.34) ALDH1A1CYP3A4TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011111054-A1 IMPROVED HAIR DYE COMPOSITION CAVINKARE PVT. LTD, (IN) 2011-09-15 WO disclosed