Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.54 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.54 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657990 | 0.94 | SLC6A2 (0.59) | SLC6A2CALCRLOPRM1OPRD1OPRK1 | |
| SCHEMBL29657941 | 0.88 | CALCRL (0.57) | SLC6A2CALCRLOPRM1OPRD1OPRK1 | |
| SCHEMBL11443805 | 0.86 | SLC6A2 (0.68) | SLC6A2OPRM1OPRD1NMUR2NMUR1 | |
| SCHEMBL29531383 | 0.86 | SLC6A2 (0.71) | SLC6A2CALCRLOPRM1OPRD1 | |
| SCHEMBL31233755 | 0.86 | SLC6A2 (0.64) | SLC6A2CALCRLOPRM1OPRD1NTSR2 | |
| SCHEMBL31247323 | 0.84 | NTSR1 (0.58) | SLC6A2CALCRLOPRM1OPRD1OPRK1 | |
| SCHEMBL31406965 | 0.84 | SLC6A2 (0.67) | SLC6A2OPRM1OPRD1NMUR2NMUR1 | |
| SCHEMBL18911387 | 0.84 | OPRD1 (0.60) | SLC6A2OPRM1OPRD1OPRK1NMUR2 | |
| SCHEMBL18911388 | 0.84 | OPRD1 (0.60) | SLC6A2OPRM1OPRD1OPRK1NMUR2 | |
| SCHEMBL30974385 | 0.84 | CALCRL (0.59) | SLC6A2CALCRLOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480534-B | Protein semisynthesis by chemoenzymatic methods based on transpeptidase | 清华大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-114480534-A | Protein semi-synthesis based on chemical enzymatic methods of transpeptidase | 清华大学 | 2022-05-13 | — | — | CN | disclosed |