Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | MET | P08581 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.57 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056256 | 1.00 | KDM4E (0.58) | KDM4EGAAMAPTL3MBTL1AURKA | |
| SCHEMBL28707400 | 0.85 | KDM4E (0.57) | KDM4EGAAMAPTL3MBTL1AURKA | |
| SCHEMBL933730 | 0.84 | KDM4E (0.47) | KDM4EGAAMAPTL3MBTL1AURKA | |
| SCHEMBL30862011 | 0.83 | KDM4E (0.72) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28892513 | 0.83 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL13090580 | 0.83 | KDM4E (0.72) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28701830 | 0.83 | MAPT (0.58) | KDM4EGAAMAPTL3MBTL1AURKA | |
| SCHEMBL28707397 | 0.81 | MAPT (0.56) | KDM4EGAAMAPTL3MBTL1NTRK1 | |
| SCHEMBL28711242 | 0.81 | KDM4E (0.55) | KDM4EGAAMAPTL3MBTL1AURKA | |
| SCHEMBL4740818 | 0.80 | AURKA (0.65) | KDM4EGAAAURKAABL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075177-B | 4-Aminofuran-2 (5H) -ketone derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114075177-A | 4-amino furan-2 (5H) -ketone derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-02-22 | — | — | CN | disclosed |