Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090580 | 1.00 | KDM4E (0.72) | KDM4EGAAL3MBTL1MAPTLTA4H | |
| SCHEMBL29442882 | 0.83 | GAA (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL21394888 | 0.83 | GAA (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29449999 | 0.83 | KDM4E (0.58) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3056256 | 0.83 | KDM4E (0.58) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL28707397 | 0.81 | MAPT (0.56) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL18919554 | 0.80 | GAA (0.69) | KDM4EGAAL3MBTL1MAPTMAOA | |
| SCHEMBL13567968 | 0.79 | GAA (0.56) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3844597 | 0.79 | LTA4H (0.59) | KDM4EGAAL3MBTL1MAPTLTA4H | |
| SCHEMBL28707400 | 0.78 | KDM4E (0.57) | KDM4EGAAL3MBTL1MAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |