Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707400 | 0.86 | KDM4E (0.57) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL21394888 | 0.85 | GAA (0.59) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL29442882 | 0.85 | GAA (0.59) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL30093193 | 0.84 | HPGD (0.52) | MAPTKDM4EGAAL3MBTL1HPGD | |
| SCHEMBL3056256 | 0.81 | KDM4E (0.58) | MAPTKDM4EGAAL3MBTL1HPGD | |
| SCHEMBL29449999 | 0.81 | KDM4E (0.58) | MAPTKDM4EGAAL3MBTL1HPGD | |
| SCHEMBL13090580 | 0.81 | KDM4E (0.72) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL30862011 | 0.81 | KDM4E (0.72) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL28701830 | 0.81 | MAPT (0.58) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL10055035 | 0.81 | HPGD (0.67) | MAPTGAAHPGDNOS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075177-B | 4-Aminofuran-2 (5H) -ketone derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114075177-A | 4-amino furan-2 (5H) -ketone derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-02-22 | — | — | CN | disclosed |