SCHEMBL29450565

SCHEMBL29450565

COC(=O)[C@H](CCSC)NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 12/20 1.00
FNTB P49356 12/20 1.00
ICMT O60725 1/20 0.86
PGGT1B P53609 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31002989 0.92 ICMT (1.00) FNTAFNTBICMTPGGT1B
SCHEMBL16136627 0.92 ICMT (1.00) FNTAFNTBICMTPGGT1B
SCHEMBL31741896 0.92 FNTA (1.00) FNTAFNTBICMTPGGT1B
SCHEMBL17548810 0.92 FNTA (1.00) FNTAFNTBICMTPGGT1B
SCHEMBL16112063 0.92 FNTA (1.00) FNTAFNTBICMTPGGT1B
Trifluoroacetic Acid SCHEMBL16111192 0.88 FNTA (0.91) FNTAFNTBICMTPGGT1B
SCHEMBL6776331 0.86 FNTA (0.75) FNTAFNTBICMT
SCHEMBL6776327 0.86 FNTA (0.75) FNTAFNTBICMT
SCHEMBL629257 0.82 FNTA (0.69) FNTAFNTBICMT
SCHEMBL629256 0.82 FNTA (0.69) FNTAFNTBICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659812-A1 DETECTION METHODS AND COMBINATION THERAPIES OF CELLS WITH EXTRACELLULAR RAS EXPRESSION Bumm, Thomas (DE) 2025-12-10 EP disclosed
US-20240285645-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV GILEAD SCIENCES, INC. 2024-08-29 US disclosed
EP-4140485-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV Gilead Sciences, Inc. (US) 2023-03-01 EP disclosed
EP-3166607-B1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV GILEAD SCIENCES INC (US) 2022-08-31 EP disclosed
US-20220062293-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV GILEAD SCIENCES, INC. 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220062293-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV TLR7, TLR3, TLR6 FNTA 3930/4885FNTB 2672/4885ICMT 3267/4885
US-20240285645-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV TLR7, TLR3, TLR6 FNTA 3930/4885FNTB 2672/4885ICMT 3267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.