Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450637 | 0.87 | POLB (0.64) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL29450622 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL6439308 | 0.81 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL29450606 | 0.81 | KMT2A (0.65) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL16982851 | 0.80 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL31224439 | 0.80 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL5641433 | 0.77 | EPHX1 (1.00) | KMT2ASMN1; SMN2MEN1EPHX1RAB9A | |
| SCHEMBL1191122 | 0.76 | CHRM3 (0.62) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL11336178 | 0.75 | RAB9A (1.00) | KMT2ASMN1; SMN2MEN1HTTEPHX1 | |
| SCHEMBL28651774 | 0.75 | KMT2A (0.79) | KMT2ASMN1; SMN2MEN1HTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022030589-A1 | LIGAND CONTAINING MONODENTATE COORDINATION UREA COMPOUND, AND BORYLATION CATALYST CONTAINING SAME | 国立大学法人北海道大学 | 2022-02-10 | — | — | WO | disclosed |