Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 10/20 | 0.43 |
| ▸ | AURKA | O14965 | 4/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450982 | 0.86 | LDHA (0.44) | P2RY14MAPK14LDHAABCG2 | |
| SCHEMBL29450908 | 0.86 | LDHA (0.41) | MAPK14LDHAESRRAABCG2 | |
| SCHEMBL29450905 | 0.85 | LDHA (0.42) | MAPK14LDHAABCG2 | |
| SCHEMBL29450967 | 0.83 | BRD4 (0.43) | P2RY14MAPK14LDHAOPRD1KCNH2 | |
| SCHEMBL29451023 | 0.82 | MAPK14 (0.41) | MAPK14LDHAABCG2 | |
| SCHEMBL29450956 | 0.82 | STIM1 (0.46) | AURKAAURKBLDHAABCG2 | |
| SCHEMBL29450966 | 0.82 | GRM5 (0.39) | AURKAMAPK14LDHAABCG2 | |
| SCHEMBL22846421 | 0.82 | GRM5 (0.39) | AURKAMAPK14LDHAABCG2 | |
| SCHEMBL29450866 | 0.81 | LDHA (0.43) | MAPK14LDHAABCG2 | |
| SCHEMBL29450888 | 0.81 | KEAP1 (0.46) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |