Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450874 | 0.93 | TP53 (0.37) | KDM4ALDHAHPGDALDH1A1LMNA | |
| SCHEMBL29450907 | 0.91 | LTB4R2 (0.40) | LDHAHPGDALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL29451036 | 0.89 | LDHA (0.38) | KDM4ALDHAHPGDALDH1A1MAPK14 | |
| SCHEMBL29450892 | 0.87 | LDHA (0.34) | LDHAMAPK14ABCB1ABCG2BRD4 | |
| SCHEMBL29450982 | 0.87 | LDHA (0.44) | LDHAMAPK14ABCB1ABCG2 | |
| SCHEMBL29450870 | 0.86 | P2RY14 (0.39) | KDM4ALDHAHPGDTDP1ALDH1A1 | |
| SCHEMBL29450996 | 0.84 | TRPC1 (0.42) | LDHATDP1ALDH1A1RECQLMAPK14 | |
| SCHEMBL29450916 | 0.84 | BRD4 (0.50) | LDHAABCB1ABCG2BRD4 | |
| SCHEMBL29450908 | 0.84 | LDHA (0.41) | LDHAHPGDALDH1A1MAPK14ABCB1 | |
| SCHEMBL29450967 | 0.84 | BRD4 (0.43) | LDHAMAPK14ABCB1ABCG2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |