Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450901 | 0.89 | KDM4A (0.39) | LDHAMAPK14ABCB1ABCG2KDM4A | |
| SCHEMBL29450982 | 0.89 | LDHA (0.44) | LDHAMAPK14KEAP1NFE2L2ABCB1 | |
| SCHEMBL29450874 | 0.87 | TP53 (0.37) | LDHAMAPK14ABCB1ABCG2KDM4E | |
| SCHEMBL29450908 | 0.86 | LDHA (0.41) | LDHAMAPK14ABCB1ABCG2MIF | |
| SCHEMBL29450967 | 0.85 | BRD4 (0.43) | LDHAMAPK14KEAP1NFE2L2ABCB1 | |
| SCHEMBL29450907 | 0.85 | LTB4R2 (0.40) | LDHAKDM4EKDM5CALDH1A1HPGD | |
| SCHEMBL29450892 | 0.85 | LDHA (0.34) | LDHAMAPK14ABCB1ABCG2MIF | |
| SCHEMBL29450968 | 0.85 | ESRRA (0.39) | LDHAABCB1ABCG2MIFSTIM1 | |
| SCHEMBL29450857 | 0.85 | ABCG2 (0.40) | LDHAMAPK14ABCB1ABCG2MIF | |
| SCHEMBL29450905 | 0.84 | LDHA (0.42) | LDHAMAPK14ABCB1ABCG2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |