Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CD74 | P04233 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450982 | 0.89 | LDHA (0.44) | MIFSTIM1ORAI1ABCG2LDHA | |
| SCHEMBL29450996 | 0.89 | TRPC1 (0.42) | ESRRASTIM1ORAI1LDHA | |
| SCHEMBL29450891 | 0.89 | GRM5 (0.38) | MIFSTIM1ORAI1ABCG2LDHA | |
| SCHEMBL29450857 | 0.87 | ABCG2 (0.40) | MIFABCG2LDHAABCB1 | |
| SCHEMBL29450956 | 0.87 | STIM1 (0.46) | AURKAAURKBSTIM1ORAI1ABCG2 | |
| SCHEMBL29450908 | 0.86 | LDHA (0.41) | ESRRAMIFSTIM1ORAI1ABCG2 | |
| SCHEMBL29450967 | 0.85 | BRD4 (0.43) | MIFSTIM1ORAI1ABCG2LDHA | |
| SCHEMBL29451015 | 0.85 | ABCG2 (0.39) | ABCG2LDHAABCB1 | |
| SCHEMBL29451036 | 0.85 | LDHA (0.38) | MIFSTIM1ORAI1ABCG2LDHA | |
| SCHEMBL29450905 | 0.84 | LDHA (0.42) | MIFABCG2LDHAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |