Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12750978 | 1.00 | HDAC8 (0.36) | HDAC8GRM5PDE2A | |
| SCHEMBL24942537 | 0.86 | EGLN2 (0.36) | HDAC8 | |
| SCHEMBL3721845 | 0.84 | — | — | |
| SCHEMBL20886074 | 0.84 | — | — | |
| SCHEMBL14155720 | 0.84 | — | — | |
| SCHEMBL24078822 | 0.80 | PDE2A (0.47) | GRM5PDE2A | |
| SCHEMBL13212470 | 0.75 | — | — | |
| SCHEMBL15442738 | 0.73 | HCAR3 (0.39) | — | |
| SCHEMBL14207104 | 0.73 | CYP1A2 (0.52) | — | |
| SCHEMBL22549179 | 0.71 | GLS (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994262-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |