SCHEMBL834744

SCHEMBL834744

CC(=O)c1ccc2cc(C(C)=O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.68
HPGD P15428 4/20 0.63
MAPT P10636 3/20 0.63
ALDH1A1 P00352 1/20 0.63
RAB9A P51151 3/20 0.55
KMT2A Q03164 3/20 0.55
NPC1 O15118 2/20 0.55
MEN1 O00255 1/20 0.55
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KDM4E B2RXH2 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 1/20 0.48
CA2 P00918 1/20 0.47
PRKCI P41743 1/20 0.47
S100A4 P26447 1/20 0.47
LCK P06239 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15105728 0.95 CYP2A6 (0.69) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL21215857 0.95 CYP2A6 (0.69) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL599006 0.92 CYP2A6 (0.79) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL29451111 0.92 CYP2A6 (0.79) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL29940036 0.91 KDM4E (0.62) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL29356637 0.91 ALDH1A1 (0.71) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL43058 0.91 ALDH1A1 (0.71) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL30678318 0.91 ALDH1A1 (0.71) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL9568286 0.91 KDM4E (0.62) CYP2A6HPGDMAPTALDH1A1RAB9A
SCHEMBL23890384 0.89 HPGD (0.58) CYP2A6HPGDMAPTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4883915-A TO AMIDES, BOROSILICATE MOLECULAR SIEVE AMOCO CORPORATION (US) 1989-11-28 US claimed
US-20230399773-A1 CORE-SHEATH COMPOSITE FIBER, PRODUCTION METHOD THEREFOR, AND FIBER STRUCTURE KURARAY CO., LTD. (JP) 2023-12-14 US disclosed
US-20230399460-A1 Liquid Crystalline Polyesters (LCP) and Thermoplastic Compositions having Low Dielectric Constant (Dk) and Dissipation Factor (Df) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-14 US disclosed
US-20230399460-A1 Liquid Crystalline Polyesters (LCP) and Thermoplastic Compositions having Low Dielectric Constant (Dk) and Dissipation Factor (Df) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-14 US disclosed
US-11807763-B2 Inkjet ink KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2023-11-07 US disclosed
US-11807023-B2 Pretreatment liquid, ink set, image recorded material, base material for image recording, method of producing base material for image recording, and image recording method FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-20230344042-A1 LIQUID CRYSTAL POLYMER BATTERY ENCLOSURE MATERIAL IONIC MATERIALS, INC. (US) 2023-10-26 US disclosed
US-20230344042-A1 LIQUID CRYSTAL POLYMER BATTERY ENCLOSURE MATERIAL IONIC MATERIALS, INC. (US) 2023-10-26 US disclosed
US-20230332334-A1 LIQUID CRYSTAL POLYESTER FIBERS AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2023-10-19 US disclosed
US-20230332350-A1 DOUBLE BRAID ROPE STRUCTURE KURARAY CO., LTD. (JP) 2023-10-19 US disclosed
US-20070102667-A1 Mechanical properties such as modulus of elongation and good molding processability at low temperatures; for producing welded articles with high joint strength; aromatic oxycarbonyl, aromatic di-carbonyl, aromatic dioxy, aromatic aminooxy, aromatic aminocarbonyl, aromatic diamino repeating units UENO TECHNOLOGY CO., LTD. 2007-05-10 US disclosed
US-7211527-B2 Resin-impregnated substrate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-01 US disclosed
US-20070077416-A1 Substrate for flexible wiring and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-05 US disclosed
US-7193020-B2 Film and laminate of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-20 US disclosed
US-7179401-B2 Thermotropic liquid-crystalline polymer KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2007-02-20 US disclosed
EP-0796835-B1 Process for the oxidation of isoalkyl-aromatic hydrocarbons and catalyst for carrying out this process RUETGERS KUREHA SOLVENTS GMBH (DE) 2000-05-17 EP disclosed
US-5990357-A CATALYTIC OXIDATION OF ISOALKYLAROMATIC HYDROCARBONS INTO KETONES, ALCOHOLS AND PEROXIDES; THESE PRODUCTS ARE VALUABLE INTERMEDIATE PRODUCTS FOR ORGANIC SYNTHESES RUTGERS KUREHA SOLVENTS GMBH (DE) 1999-11-23 US disclosed
EP-0796835-A1 Process for the oxidation of isoalkyl-aromatic hydrocarbons and catalyst for carrying out this process Rütgers Kureha Solvents GmbH (DE) 1997-09-24 EP disclosed
US-4883915-A TO AMIDES, BOROSILICATE MOLECULAR SIEVE AMOCO CORPORATION (US) 1989-11-28 US disclosed
US-4697010-A TO CYCLIC AMIDES AMOCO CORPORATION (US) 1987-09-29 US disclosed