Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319511 | 0.82 | ALDH1A1 (0.56) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL29451590 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL11068177 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALDH1A1ALOX15 | |
| SCHEMBL11471560 | 0.80 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1CCNT1 | |
| SCHEMBL12776234 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL22500869 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL29670437 | 0.76 | ALOX5 (0.47) | MEN1KMT2AMAPTALDH1A1CCNT1 | |
| SCHEMBL20202311 | 0.76 | ALDH1A1 (0.66) | MEN1KMT2AMAPTALDH1A1ALOX15 | |
| SCHEMBL11773684 | 0.76 | MAPK1 (0.47) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4980377 | 0.75 | ALDH1A1 (0.57) | MEN1KMT2AMAPTALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032144-A1 | SUBSTRATE ADAPTOR INHIBITORS OF PRMT5 AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-02-10 | — | — | WO | disclosed |