Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948725 | 0.79 | IDO1 (1.00) | IDO1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL29620841 | 0.77 | IDO1 (0.54) | IDO1MAPTSMN1; SMN2ALOX15MEN1 | |
| SCHEMBL1438848 | 0.77 | IDO1 (0.58) | IDO1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL14198211 | 0.69 | MAPT (0.51) | IDO1MAPTSMN1; SMN2ALOX15HPGD | |
| SCHEMBL28029281 | 0.68 | SMN1; SMN2 (0.61) | IDO1MAPTSMN1; SMN2ALOX15HPGD | |
| SCHEMBL6907528 | 0.67 | IDO1 (0.50) | IDO1MAPTSMN1; SMN2HPGDMEN1 | |
| SCHEMBL17376580 | 0.66 | ASIC3 (0.44) | IDO1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL17938574 | 0.66 | MEN1 (0.78) | MAPTSMN1; SMN2ALOX15HPGDNFKB1 | |
| SCHEMBL12543941 | 0.66 | IDO1 (0.74) | IDO1MAPTSMN1; SMN2HPGDCYP11B1 | |
| SCHEMBL4051570 | 0.66 | CA2 (0.48) | MAPTCYP11B1CYP11B2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204020-A1 | METHOD OF TREATING PSMA-EXPRESSING CANCERS | Advanced Accelerator Applications International S.A. (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043558-A1 | METHOD OF TREATING PSMA-EXPRESSING CANCERS | ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL SA (CH) | 2022-03-03 | — | — | WO | disclosed |