SCHEMBL24379045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30353939	1.00	TSHR (0.47)	TSHRUCHL1MAOBMAOACDC25B
	SCHEMBL29518456	1.00	TSHR (0.47)	TSHRUCHL1MAOBMAOACDC25B
	SCHEMBL4975695	0.85	ALDH1A1 (0.47)	TSHRALDH1A1KDM4EHSD17B10LMNA
	SCHEMBL29453753	0.83	TSHR (0.57)	TSHRUCHL1MAOBCDC25BALDH1A1
	SCHEMBL11662	0.83	TSHR (0.57)	TSHRUCHL1MAOBCDC25BALDH1A1
	SCHEMBL30168056	0.81	UCHL1 (0.46)	TSHRUCHL1ALDH1A1KDM4EGLA
	SCHEMBL19893995	0.81	UCHL1 (0.43)	TSHRUCHL1ALDH1A1KDM4EGAA
	SCHEMBL24840045	0.81	UCHL1 (0.46)	TSHRUCHL1ALDH1A1KDM4EGLA
	SCHEMBL24378834	0.81	TSHR (0.46)	TSHRUCHL1MAOBMAOACDC25B
	SCHEMBL29518411	0.81	TSHR (0.46)	TSHRUCHL1MAOBMAOACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.