SCHEMBL29454271

SCHEMBL29454271

Cc1cc(N)c(C)c(Cc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
IDH1 O75874 2/20 0.44
HTR2A P28223 1/20 0.41
CALM1 P0DP23 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
GPR55 Q9Y2T6 1/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232131 1.00 BCL2 (0.44) BCL2BCL2L1IDH1HTR2ACALM1
SCHEMBL23295585 0.87 IDH1 (0.42) BCL2BCL2L1IDH1HTR2ACALM1
SCHEMBL22232155 0.86 TDP1 (0.41) CYP3A4
SCHEMBL22231801 0.85 TAAR1 (0.47) CYP3A4
SCHEMBL9494600 0.85 BCL2 (0.44) BCL2BCL2L1HTR2ACALM1GPR55
SCHEMBL28049389 0.84 BCL2 (0.47) BCL2BCL2L1IDH1HTR2ACALM1
SCHEMBL22232349 0.84 CYP3A4 (0.41) BCL2BCL2L1IDH1HTR2ACALM1
SCHEMBL14303046 0.84 BCL2 (0.48) BCL2BCL2L1ALOX5
SCHEMBL29454241 0.84 CYP3A4 (0.41) BCL2BCL2L1IDH1HTR2ACALM1
SCHEMBL22231978 0.83 TAAR1 (0.42) CYP3A4GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS BCL2 1141/4885BCL2L1 1762/4885IDH1 592/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS BCL2 1839/4885BCL2L1 1629/4885IDH1 626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.