SCHEMBL29454241

SCHEMBL29454241

Cc1cc(N)c(Cl)c(Cc2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
IDH1 O75874 2/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ADCY10 Q96PN6 1/20 0.39
HTR2A P28223 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
CALM1 P0DP23 1/20 0.37
CTRC Q99895 2/20 0.37
NOS3 P29474 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232349 1.00 CYP3A4 (0.41) CYP3A4MEN1HPGDALOX15KMT2A
SCHEMBL22232238 0.88 CYP3A4 (0.38) CYP3A4MEN1ALOX15KMT2AHSD17B10
SCHEMBL22231866 0.87 MPO (0.44) CYP3A4HPGDHSD17B10CYP2C19
SCHEMBL22232545 0.85 PNMT (0.44) CYP3A4ADCY10
SCHEMBL22232185 0.85 TAAR1 (0.39) CYP3A4HPGDALOX15HIF1AHSD17B10
SCHEMBL22231954 0.84 MPO (0.40) CYP3A4ALOX15HIF1AHSD17B10IDH1
SCHEMBL22232131 0.84 BCL2 (0.44) CYP3A4IDH1BCL2BCL2L1HTR2A
SCHEMBL29454271 0.84 BCL2 (0.44) CYP3A4IDH1BCL2BCL2L1HTR2A
SCHEMBL22232016 0.83 ADCY10 (0.41) CYP3A4ADCY10GPR55
SCHEMBL22231931 0.83 MAPT (0.36) CYP3A4HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS CYP3A4 412/4885MEN1 1657/4885HPGD 4107/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS CYP3A4 264/4885MEN1 3874/4885HPGD 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.