Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972568 | 0.95 | MEN1 (0.45) | NPC1RAB9ASGMS1KMT2AHPGD | |
| SCHEMBL12568257 | 0.91 | RAB9A (0.43) | NPC1RAB9ATP53KMT2AMEN1 | |
| SCHEMBL26687954 | 0.90 | NPC1 (0.42) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL14537676 | 0.90 | NPC1 (0.41) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL14123991 | 0.89 | NPC1 (0.44) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL31146900 | 0.89 | KMT2A (0.45) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL29368397 | 0.89 | KMT2A (0.45) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL29470540 | 0.89 | KMT2A (0.45) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL3367289 | 0.89 | KMT2A (0.45) | NPC1RAB9ATP53KMT2AHPGD | |
| SCHEMBL1745934 | 0.89 | KMT2A (0.45) | NPC1RAB9ATP53KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11472844-B2 | Peptidomimetics, method of synthesis and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-10-18 | — | — | US | disclosed |
| EP-3724215-B1 | PEPTIDOMIMETICS, METHOD OF SYNTHESIS AND USES THEREOF | PASTEUR INSTITUT (FR) | 2022-04-13 | — | — | EP | disclosed |