Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12568257 | 0.93 | RAB9A (0.43) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL5813924 | 0.92 | NPC1 (0.43) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL14537676 | 0.91 | NPC1 (0.41) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL14123991 | 0.91 | NPC1 (0.44) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL29454419 | 0.90 | NPC1 (0.45) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL14360219 | 0.90 | NPC1 (0.43) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL1745934 | 0.89 | KMT2A (0.45) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL14416300 | 0.89 | KMT2A (0.42) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL29470540 | 0.89 | KMT2A (0.45) | NPC1RAB9AMDM2KMT2AMEN1 | |
| SCHEMBL29368397 | 0.89 | KMT2A (0.45) | NPC1RAB9AMDM2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219933-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS | ENTRADA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-113861268-A | Cell penetrating peptides and methods of making and using the same | 恩特拉达治疗学股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-106852146-B | Cell penetrating peptides and methods of making and using the same | 恩特拉达治疗学股份有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-107440928-A | Cosmetic composition for improving scalp health and method for producing the same | 奥利博思高适美秀迪科思 | 2017-12-08 | — | — | CN | disclosed |
| CN-106852146-A | Cell penetrating peptides and methods of making and using the same | 塞克洛波特斯公司 | 2017-06-13 | — | — | CN | disclosed |