Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454543 | 0.85 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL22717447 | 0.85 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL22717448 | 0.85 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL29454586 | 0.82 | FFAR1 (0.43) | FFAR1MAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL22717404 | 0.82 | FFAR1 (0.43) | FFAR1MAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL22717401 | 0.82 | FFAR1 (0.43) | FFAR1MAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL29454653 | 0.81 | RAB9A (0.49) | MAPTTDP1FFAR1ALDH1A1KMT2A | |
| SCHEMBL21688300 | 0.78 | FFAR1 (0.56) | FFAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL22717243 | 0.77 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL22717523 | 0.77 | FFAR1 (0.64) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976576-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |