Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717401 | 0.84 | FFAR1 (0.43) | KMT2AALDH1A1KDM4EFFAR1F2 | |
| SCHEMBL22717404 | 0.84 | FFAR1 (0.43) | KMT2AALDH1A1KDM4EFFAR1F2 | |
| SCHEMBL29454586 | 0.84 | FFAR1 (0.43) | KMT2AALDH1A1KDM4EFFAR1F2 | |
| SCHEMBL29454565 | 0.82 | FFAR1 (0.59) | KMT2ASMN1; SMN2FFAR1 | |
| SCHEMBL21644935 | 0.82 | FFAR1 (0.59) | KMT2ASMN1; SMN2FFAR1 | |
| SCHEMBL20103667 | 0.82 | FFAR1 (0.59) | KMT2ASMN1; SMN2FFAR1 | |
| SCHEMBL29454654 | 0.81 | MAPT (0.49) | TDP1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL21688300 | 0.79 | FFAR1 (0.56) | RAB9AKMT2AALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL22717051 | 0.79 | ALDH1A1 (0.43) | RAB9AKMT2ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29454590 | 0.79 | ALDH1A1 (0.43) | RAB9AKMT2ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220226298-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2022-07-21 | — | — | US | disclosed |
| EP-3976576-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220226298-A1 | GPR40 AGONISTS | GPR119, GPR65, GLP1R | RAB9A 2945/4885TDP1 4444/4885KMT2A 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.