Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379856 | 1.00 | EPHX1 (0.43) | EPHX1GAAALDH1A1POLBTSHR | |
| SCHEMBL379857 | 1.00 | EPHX1 (0.43) | EPHX1GAAALDH1A1POLBTSHR | |
| SCHEMBL2941952 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2941951 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17872626 | 0.74 | SMYD3 (0.40) | EPHX1GAAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17872624 | 0.74 | SMYD3 (0.40) | EPHX1GAAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5792200 | 0.73 | — | — | |
| SCHEMBL26106230 | 0.73 | POLB (0.46) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL26106226 | 0.73 | POLB (0.46) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL9885094 | 0.73 | ALDH1A1 (0.78) | EPHX1GAAALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737161-B2 | Condensed furan compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090156803-A1 | Condensed furan compounds | KAWAGUCHI TAKAYUKI | 2009-06-18 | — | — | US | disclosed |
| US-7531537-B2 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| CN-100475777-C | Amide type carboxamide derivative | TANABE SEIYAKU CO (JP) | 2009-04-08 | — | — | CN | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7375119-B2 | Amide type carboxamide derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| CN-100344632-C | Fused furan compound | TANABE SEIYAKU CO (JP) | 2007-10-24 | — | — | CN | disclosed |
| US-20060287329-A1 | Amide type carboxamide derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-12-21 | — | — | US | disclosed |
| CN-1860097-A | Amide-type carboxamide derivative | TANABE SEIYAKU CO (JP) | 2006-11-08 | — | — | CN | disclosed |
| EP-1666455-A1 | AMIDE TYPE CARBOXAMIDE DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20060094724-A1 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1723210-A | Fused furan compound | TANABE SEIYAKU CO (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-20050282808-A1 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-12-22 | — | — | US | disclosed |
| EP-1582521-A1 | FUSED FURAN COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-1489078-A1 | BENZOFURAN DERIVATIVE | Tanabe Seiyaku Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282808-A1 | Benzofuran derivative | F12, F2, F11 | EPHX1 3082/4885GAA 3882/4885ALDH1A1 683/4885 |
| US-20060287329-A1 | Amide type carboxamide derivative | F12, F11, F13A1 | EPHX1 3109/4885GAA 2610/4885ALDH1A1 884/4885 |
| US-20090156803-A1 | Condensed furan compounds | F2, F12, F11 | EPHX1 923/4885GAA 4223/4885ALDH1A1 1627/4885 |
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | EPHX1 3031/4885GAA 3844/4885ALDH1A1 693/4885 |
| US-20060094724-A1 | Fused furan compound | F2, F12, F11 | EPHX1 918/4885GAA 4234/4885ALDH1A1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.