SCHEMBL294552

SCHEMBL294552

CCOC(=O)C1C(C=C(Cl)Cl)C1(C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.75
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 4/20 0.49
ATM Q13315 2/20 0.49
ADRA2A P08913 1/20 0.49
CNR1 P21554 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11444513 1.00 LMNA (0.75) LMNATSHRTDP1ATMADRA2A
SCHEMBL10828657 1.00 LMNA (0.75) LMNATSHRTDP1ATMADRA2A
SCHEMBL10778297 1.00 LMNA (0.75) LMNATSHRTDP1ATMADRA2A
SCHEMBL10837019 0.89 LMNA (0.65) LMNATSHRTDP1ATMADRA2A
SCHEMBL3690536 0.88 LMNA (0.69) LMNATSHRTDP1ATMADRA2A
SCHEMBL3690534 0.88 LMNA (0.69) LMNATSHRTDP1ATMADRA2A
SCHEMBL294548 0.86 LMNA (0.57) LMNATSHRTDP1ATMADRA2A
SCHEMBL10948910 0.86 LMNA (0.75) LMNATSHRTDP1ATMADRA2A
Chrysanthemic Acid, Ethyl Ester SCHEMBL6054986 0.86 LMNA (1.00) LMNATSHRTDP1ATMADRA2A
Chrysanthemic Acid, Ethyl Ester SCHEMBL10712272 0.86 LMNA (1.00) LMNATSHRTDP1ATMADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242778-B1 SEPARATION OF DIASTEREO ISOMERS BAYER AG (DE) 1989-09-13 EP claimed
US-10647655-B2 Method for the synthesis of permethrin BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2020-05-12 US disclosed
EP-3506748-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN Biophore India Pharmaceuticals Pvt. Ltd. (IN) 2019-07-10 EP disclosed
US-20190194118-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2019-06-27 US disclosed
US-20190190720-A1 SECURING AN ITEM OF DEVICE USE INFORMATION OF A DEVICE SIEMENS AKTIENGESELLSCHAFT (DE) 2019-06-20 US disclosed
US-20170020900-A1 METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF NIH - DEITR 2017-01-26 US disclosed
US-20170020900-A1 METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF NIH - DEITR 2017-01-26 US disclosed
US-9301940-B2 Methods for screening antimicrobial and antiviral compounds and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2016-04-05 US disclosed
US-9301940-B2 Methods for screening antimicrobial and antiviral compounds and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2016-04-05 US disclosed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP disclosed
EP-0001847-A1 Process for the preparation of alkenyl cyanoacetates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-05-16 EP disclosed
US-4138584-A Production of chrysanthemic acid esters and homologues thereof A/S CHEMINOVA (DK) 1979-02-06 US disclosed
US-4116998-A Preparation of esters of m-phenoxybenzyl alcohol and its α-cyano and α-ethinyl derivatives with 2,2-dimethylcyclopropanecarboxylic acids IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-09-26 US disclosed
US-4117247-A THERMAL ISOMERIZATION KURARAY CO., LTD. (JP) 1978-09-26 US disclosed
US-4113969-A PREPARATION OF 2,2-DIMETHYL-3-(2,2-DIHALOGENOVINYL)-CYCLOPROPANE-1-CARBOXYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed
US-4113968-A FROM A 1-HALO-3-ALKENE-2-OL KURARAY CO., LTD. (JP) 1978-09-12 US disclosed
US-4102896-A Preparation of a 5-(2,2-dihalovinyl)-4,4-dimethyl-2-oxotetrahydrofuran IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-07-25 US disclosed
US-4081488-A FRIEDEL CRAFTS CONDENSATION OF VINYLIDENE CHLORIDE AND ISOBUTYRYL CHLORIDE, REDUCTION, DEHYDRATION FMC CORPORATION (US) 1978-03-28 US disclosed
US-4070404-A Process to 1,1-dihalo-4-methyl-1,3-pentadienes, pyrethroid insecticide intermediates FMC CORPORATION (US) 1978-01-24 US disclosed
US-4022672-A Electrochemical synthesis of insecticide intermediates FMC CORPORATION (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170020900-A1 METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF ZC3HAV1, MAVS, EIF2AK2 LMNA 2719/4885TSHR 4677/4885TDP1 2033/4885
US-10647655-B2 Method for the synthesis of permethrin NUP188, CYP2E1, AQP4 LMNA 2817/4885TSHR 2372/4885TDP1 2093/4885
US-20190194118-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN CYP51A1, CYP4F3, CYP4F2 LMNA 4054/4885TSHR 3197/4885TDP1 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.