Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.58 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945529 | 1.00 | SCD (0.58) | SCDGLSSCD5KDM4ENPC1 | |
| SCHEMBL2951628 | 0.81 | SCD (0.89) | SCDSCD5 | |
| SCHEMBL2940781 | 0.79 | SCD (0.60) | SCDSCD5 | |
| SCHEMBL27765327 | 0.78 | SCD (0.60) | SCDSCD5 | |
| SCHEMBL473031 | 0.78 | SCD (0.62) | SCDSCD5 | |
| SCHEMBL473035 | 0.78 | SCD (0.59) | SCDSCD5 | |
| SCHEMBL473034 | 0.78 | SCD (0.59) | SCDSCD5 | |
| SCHEMBL2946619 | 0.77 | SCD (0.57) | SCDSCD5 | |
| SCHEMBL473036 | 0.76 | SCD (0.62) | SCDSCD5 | |
| SCHEMBL17654151 | 0.76 | GLS (0.57) | GLSKDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754745-B2 | Azacyclopentane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-07-13 | — | — | US | disclosed |
| US-20090093527-A1 | Azacyclopentane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. (CA) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093527-A1 | Azacyclopentane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | SCD, SCD5, SREBF1 | SCD 1/4885GLS 904/4885SCD5 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.