SCHEMBL433669

SCHEMBL433669

CCOC[CH]COC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL605471 0.87
SCHEMBL491153 0.80
SCHEMBL11797693 0.77
SCHEMBL11797697 0.77
SCHEMBL915207 0.76
SCHEMBL5867193 0.76
SCHEMBL618804 0.75
SCHEMBL11794541 0.74 HSD17B10 (0.33)
SCHEMBL6636192 0.74 CA2 (0.30)
SCHEMBL615246 0.73 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060025434-A1 Therapeutic agents for drug/substance dependence TORAY INDUSTRIES, INC. (JP) 2006-02-02 US claimed
US-4855311-A DERIVATIVES OF BENZOISOTHIAZOLE OXIME AGRO-KANESHO CO., LTD. (JP) 1989-08-08 US claimed
US-9375008-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2016-06-28 US disclosed
US-9247745-B2 Substituted pyridazines for controlling invertebrate pests BASF SE (DE) 2016-02-02 US disclosed
EP-2342196-B1 PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2015-07-29 EP disclosed
US-9040537-B2 Pyridazine compounds for controlling invertebrate pests BASF SE (DE) 2015-05-26 US disclosed
EP-2595981-B1 NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2014-12-10 EP disclosed
US-20140142111-A1 Pyrazole Compounds for Controlling Invertebrate Pests BASF SE (DE) 2014-05-22 US disclosed
US-8729083-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2014-05-20 US disclosed
EP-2595981-A1 NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2013-05-29 EP disclosed
US-20130116264-A1 Novel Hetaryl (thio)carboxamide Compounds for Controlling Invertebrate Pests BASF SE (DE) 2013-05-09 US disclosed
US-6096741-A FUNGICIDES, TACHYKININ ANTAGONIST SHIONOGI & CO., LTD. (JP) 2000-08-01 US disclosed
EP-0808111-B1 A LOW PHOSPHORUS ANIMAL FEED CONTAINING 1 -ALPHA- HYDROXYLATED VITAMIN D COMPOUNDS WISCONSIN ALUMNI RES FOUND (US) 1999-09-01 EP disclosed
EP-0913376-A1 Process for the preparation of cyclohexanones MERCK PATENT GmbH (DE) 1999-05-06 EP disclosed
US-5719155-A CARDIOVASCULAR DISORDERS JAPAN TOBACCO INC. (JP) 1998-02-17 US disclosed
EP-0677519-A1 CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF Japan Tobacco Inc. (JP) 1995-10-18 EP disclosed
US-5047432-A Antidepressants THE BOOTS COMPANY PLC (GB) 1991-09-10 US disclosed
EP-0438261-A2 Condensed heterocyclic glutamic acid derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-07-24 EP disclosed
US-4925879-A ANTIDEPRESSANTS BOOTS COMPANY, PLC (GB) 1990-05-15 US disclosed
EP-0191542-A1 Arylcyclobutylalkyl amines and their use as antidepressive medicines The Boots Company PLC (GB) 1986-08-20 EP disclosed